Cardiovascular Diabetology | Full text | Safety and tolerability of …

These studies were multicentre, randomised , double-blind, placebo- controlled studies comparing canakinumab with placebo in T2DM patients, on stable metformin monotherapy (except for one study [26] that comprised five strata: T2DM + ….. The observed safety findings and overall tolerability in patients with T2DM are consistent with those in previously reported studies in patients with cryopyrin-associated periodic syndrome, gouty arthritis and systemic juvenile …

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Cardiovascular Diabetology | Full text | Safety and tolerability of …

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